Tel. +44 (0)20 8722 4122

Fax. +44 (0)20 8722 4359

Email. tgl@icr.ac.uk

Laboratory Address:

TGLclinical

Institute of Cancer Research

15 Cotswold Road

Sutton SM2 5NG

UNITED KINGDOM

TGLclinical ICR_F_Col

The Institute of Cancer Research: Royal Cancer Hospital

Company Limited by Guarantee. Registered in England No. 534147.

A Charity, Not for Profit, VAT Registration No. GB 849 0581 02

ICR Registered Address:

123 Old Brompton Road; London; SW7 3RP

Logo_for website

BRCA1 & BRCA2 full gene analysis

Target turnaround time: 4 weeks

90% of tests are reported within 3 weeks

Price: £355

Testing for familial mutations in cancer predisposition genes

Target turnaround time: 14 - 28 days

Price: £132      95% reported within 6 weeks

TGLclinical Clinical Consultants offer extensive clinical experience and research expertise

 

Cancer Predisposition Genes (CPG)

 

High depth (median 1000x) NGS sequencing with bespoke analytical and interpretative pipelines involving genetic and clinical genetic experts. All classes of variants are detected including base substitutions, indels and exon deletion/duplications. All variants are fully interpreted with clear information regarding clinical relevance (VUS rate <0.5%). Clear information about clinical actionability is provided for all reported variants.

Lynch Syndrome

MLH1, MSH2 & MSH6, PMS2, EPCAM

Price: £430      95% reported within 6 weeks

Paraganglioma / Pheochromocytoma

SDHB, SDHC, SDHD, SDHAF2, MAX, NF1, RET, TMEM127, VHL

Price: £430       95% reported within 6 weeks

Polyposis

APC, MUTYH

Price: £430     95% reported within 6 weeks

Renal

BAP1, FH, FLCN, MET, PTEN, SDHB, VHL

Price: £430       95% reported within 6 weeks

Melanoma

CDK4, CDKN2A

Price: £430      95% reported within 6 weeks

CPG-21

APC, ATM, BRCA1, BRCA2, BRIP1, CDH1, CHK2, EPCAM, MLH1, MSH2, MSH6, MUTYH, PALB2, PMS2, POLD1, POLE, PTEN, RAD51C, RAD51D, STK11, TP53

Price: £430     95% reported within 6 weeks

Any other CPG single gene test

Target turnaround time: 6 weeks

80% of tests are reported within 4 weeks

Price: £355